ASPIRE Awards for High-Impact Cancer Research

About this program

The Mark Foundation for Cancer Research offers ASPIRE Awards to support high-risk, high-reward cancer research addressing feasibility and proof-of-concept questions, spanning basic, translational, technology, and early-stage clinical research. ASPIRE I provides up to $250,000 for 12 months or less, while ASPIRE II provides up to $750,000 for projects lasting up to 36 months; clinical studies may receive extended periods or larger budgets. The program supports researchers worldwide, including collaborations, and requires principal investigators to be independent researchers at their institutions. Proposals are generally submitted in response to focused requests for proposals or considered by invitation, with awards selected through rigorous scientific and impact-focused review.