Addressing Health Outcomes for Individuals With Intellectual and Developmental Disabilities (IDD) and/or Rare Diseases (RD) PCORI Funding Announcement -- Cycle 3 2026

About this program

The Patient-Centered Outcomes Research Institute (PCORI) issues multiple funding announcements each year to support patient-centered comparative clinical effectiveness research (CER), related methods studies, engagement activities, and dissemination and implementation of PCORI-funded findings. Opportunities are organized across recurring cycles and funding tracks (research, engagement, dissemination), with posted LOI and application deadlines, occasional limited/invitation-only calls, and guidance resources including standard due dates and submission instructions. Eligible applicants include investigators, academic and research institutions, health systems, community and patient organizations, and other entities capable of conducting CER; most awards require meaningful patient and stakeholder engagement and compliance with program‑specific eligibility, LOI submission limits, and proposal requirements.