foundation

Patient-Centered Outcomes Research Institute

www.pcori.org (opens in a new tab)22 open · 2 closedCatalog updated

Open programs22

  1. Engagement Award: Capacity Building — Fall 2026 Cycle

    The Patient-Centered Outcomes Research Institute (PCORI) offers Engagement Award: Capacity Building grants to strengthen the skills and capacity of patients, families, caregivers, healthcare community members, and researchers to participate meaningfully in patient-centered comparative clinical effectiveness research (CER).

    Research ProjectHealth

    Deadline
    Letter of intent
    Amount
    $300,000

  2. Addressing Health Outcomes for Individuals With Intellectual and Developmental Disabilities (IDD) and/or Rare Diseases (RD) PCORI Funding Announcement -- Cycle 3 2026

    The Patient-Centered Outcomes Research Institute (PCORI) issues multiple funding announcements each year to support patient-centered comparative clinical effectiveness research (CER), related methods studies, engagement activities, and dissemination and implementation of PCORI-funded findings.

    Research ProjectHealth

    Deadline
    Letter of intent
    Amount
    Not listed

  3. Addressing Substance Use PCORI Funding Announcement -- Cycle 3 2026

    The Patient-Centered Outcomes Research Institute (PCORI) will issue a Funding Announcement on Aug.

    Research ProjectHealth

    Deadline
    Letter of intent
    Amount
    $60,000,000

  4. Advancing the Science of Engagement in Research (PCORI PFA Cycle 3 2026)

    The Patient-Centered Outcomes Research Institute (PCORI) will issue a Funding Announcement on Aug 4, 2026 to support research that builds evidence on engagement in research, including development of measures/assessment strategies for engagement structure, process, and outcomes and development/testing of engagement methods across contexts.

    Research ProjectHealth

    Deadline
    Letter of intent
    Amount
    $1,500,000

  5. Broad Pragmatic Studies PCORI Funding Announcement — Cycle 3 2026

    The Patient-Centered Outcomes Research Institute (PCORI) will issue a Broad Pragmatic Studies (BPS) funding announcement on Aug 4, 2026 to support high‑impact, patient‑centered comparative clinical effectiveness research (CER) that compares at least two treatments, services, or care‑delivery strategies; Cycle 3 highlights include perinatal mental health and substance use, cancer survivorship, diabetes prevention/care, and management of neuropathic pain (including pain in people with IDD/ADRD).

    Research ProjectHealth

    Deadline
    Letter of intent
    Amount
    $120,000,000

  6. Implementation of Findings From PCORI's Research Investments PCORI Funding Announcement -- Cycle 3 2026

    The Patient-Centered Outcomes Research Institute (PCORI) will release an open-competition Funding Announcement (Cycle 3 2026) to support implementation projects that promote uptake of published, peer‑reviewed findings from selected PCORI-funded comparative clinical effectiveness research and systematic reviews into practice to improve health care and outcomes.

    Research ProjectHealth

    Deadline
    Letter of intent
    Amount
    $1,800,000

  7. Improving Methods for Conducting Patient-Centered Comparative Clinical Effectiveness Research (Methods) PFA — Cycle 3 2026

    The Patient-Centered Outcomes Research Institute (PCORI) will issue a Methods PFA (Cycle 3 2026) to fund studies that address high-impact methodological gaps in patient-centered comparative clinical effectiveness research (CER), prioritizing patient-centered measurement, the use of real-world data in multi-site CER, AI/ML methods, and study design improvements.

    Research ProjectHealth

    Deadline
    Letter of intent
    Amount
    $12,000,000

  8. PCORI Limited Competition: Implementation Awards — Cycle 3 2026

    The Patient-Centered Outcomes Research Institute (PCORI) will release a Limited Competition Funding Announcement (Implementation Awards — Cycle 3 2026) to support projects that implement, disseminate, or plan implementation of evidence from PCORI-funded patient-centered comparative effectiveness research in real-world practice settings.

    Research ProjectHealth

    Deadline
    Letter of intent
    Amount
    $1,800,000

  9. PCORI PFA: Addressing Health Outcomes for Individuals With IDD and/or Rare Diseases (Cycle 3 2026)

    The Patient-Centered Outcomes Research Institute (PCORI) will issue a Funding Announcement on Aug.

    Research ProjectHealth

    Deadline
    Letter of intent
    Amount
    $60,000,000

  10. Substance Use PCORI Funding Announcement -- Cycle 3 2026

    The Patient-Centered Outcomes Research Institute (PCORI) will issue a Funding Announcement on Aug.

    Research ProjectHealth

    Deadline
    Letter of intent
    Amount
    $60,000,000

  11. Client Challenge

    The Patient-Centered Outcomes Research Institute (PCORI) invites applications for large-scale research grants to enhance patient-centered comparative clinical effectiveness research.

    Other

    Deadline
    Not listed
    Amount
    $120,000,000

  12. Client Challenge

    The Patient-Centered Outcomes Research Institute (PCORI) will open a Methods Funding Announcement on April 1, 2026 to support studies that address high-impact methodological gaps in patient-centered comparative clinical effectiveness research, with program priorities including patient-centered measurement, use of real-world data in multi-site CER, AI/ML methods, and study design.

    Other

    Deadline
    Not listed
    Amount
    $12,000,000

  13. Eugene Washington PCORI Engagement Award: Capacity Building

    The Patient-Centered Outcomes Research Institute (PCORI), an independent nonprofit and leading funder of patient-centered comparative clinical effectiveness research, offers Engagement Awards: Capacity Building to strengthen patients’, stakeholders’, and researchers’ skills and capacity for meaningful participation in patient-centered CER.

    Research Project

    Deadline
    Not listed
    Amount
    $300,000

  14. Eugene Washington PCORI Engagement Award: Capacity Building (Spring 2025 Cycle)

    The Patient-Centered Outcomes Research Institute (PCORI) offers up to $25 million through its Eugene Washington PCORI Engagement Award: Capacity Building program to strengthen patients’, families’, caregivers’, and healthcare community members’ ability to participate meaningfully in patient-centered comparative clinical effectiveness research.

    Research Project

    Deadline
    Not listed
    Amount
    $25,000,000

  15. Eugene Washington PCORI Engagement Award: Convening Support

    The Patient-Centered Outcomes Research Institute (PCORI) offers Eugene Washington PCORI Engagement Awards of up to $125,000 for one-year projects convening patients, families, caregivers, and other healthcare stakeholders to advance patient-centered comparative clinical effectiveness research or disseminate eligible PCORI-funded findings.

    Workshop/Conference

    Deadline
    Not listed
    Amount
    $125,000

  16. Eugene Washington PCORI Engagement Award: Dissemination Initiative

    The Patient-Centered Outcomes Research Institute (PCORI) offers the Eugene Washington PCORI Engagement Award: Dissemination Initiative to support active, targeted communication of PCORI-funded patient-centered comparative effectiveness research findings to patients, families, caregivers, clinicians, and other healthcare stakeholders.

    Research Project

    Deadline
    Not listed
    Amount
    $300,000

  17. Eugene Washington PCORI Engagement Award: Stakeholder Convening Support

    The Patient-Centered Outcomes Research Institute (PCORI) offers Eugene Washington PCORI Engagement Awards of up to $125,000 for one-year projects that convene patients, families, caregivers, and other stakeholders to advance patient-centered comparative clinical effectiveness research or disseminate eligible PCORI-funded findings.

    Workshop/Conference

    Deadline
    Not listed
    Amount
    $125,000

  18. Partnering Research and Community Organizations for Comparative Clinical Effectiveness Research Across the Cancer Care Continuum (The Cancer Partner PFA) — Cycle 1 2026

    The Patient-Centered Outcomes Research Institute (PCORI) offers up to $60 million for comparative clinical effectiveness research in cancer care.

    Research ProjectHealth

    Deadline
    Not listed
    Amount
    $60,000,000

  19. PCORI Ambassador Program

    The Patient-Centered Outcomes Research Institute (PCORI) offers a unique volunteer opportunity, the Ambassador Program, to engage healthcare professionals and enthusiasts in patient-centered research.

    OtherHealth

    Deadline
    Not listed
    Amount
    Not listed

  20. PCORI Ambassador Program

    Patient-Centered Outcomes Research Institute (PCORI) operates the PCORI Ambassador Program, a national volunteer network that engages the healthcare community to strengthen patient-centered comparative clinical effectiveness research (CER) and disseminate PCORI-funded findings.

    OtherHealth

    Deadline
    Not listed
    Amount
    Not listed

  21. PCORI Funding Announcement: Retrospective Observational Comparative Clinical Effectiveness Research (Cycle 1 2026)

    The Patient-Centered Outcomes Research Institute (PCORI) offers a grant opportunity for retrospective observational studies, aiming to enhance healthcare decision-making and patient outcomes.

    Research ProjectHealth

    Deadline
    Not listed
    Amount
    $25,000,000

  22. PCORI Funding Opportunities

    The Patient-Centered Outcomes Research Institute (PCORI) provides funding opportunities for research studies and engagement projects focused on patient-centered outcomes research, addressing areas such as cancer, cardiovascular disease, and rare diseases.

    Research ProjectHealth

    Deadline
    Not listed
    Amount
    Not listed
2 closed programsDeadline passed before Sep 21, 2026

  1. BPS Supplemental Funding Announcement (Cycle 2 2026) — Measures to Advance the Science of Engagement in Research (Invitation Only)

    Closed
    Amount
    $10,000,000

  2. PCORI Call for Proposals for HSII Implementation Projects -- 2026

    Closed
    Amount
    $2,500,000

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